Juvenile Cataract

Juvenile Cataract is an autosomal recessive disorder of an eye, characterized by opacity or light scattering in the lens of the eye leading to visual impairment or blindness in the affected dogs. It is caused by alterations of lens homeostasis due to accumulation of high-molecular-weight protein aggregations or a disarray in the organization of lens fiber cells due to aberrations during development or growth. Clinical signs in Wirehaired Pointing Griffon appear at approximately 8 weeks of age.

Inheritance: autosomal recessive

Mutation: FYCO1 gene

Genetic test: The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.