E-Lokus
E-Lokus

E-Locus

€49,00
SKU: 2700109

Melanocortin 1 receptor (MC1R) on E-Locus is responsible for regulation of pigment production in melanocytes. Mutation inMC1R gene results in non-functional receptor and switches pigment production to pheomelanin. Because production of eumelanin is disabled, effect of other loci is not possible. Mutation is recessive therefore, two such alleles are necessary for yellow-red (pheomelanin) coat colour expression. Different dog breeds with genotype e/e express different colour shades from light cream (Golden Retriever) to deep red (Irish Setter). E-Locus does not interfere with pigment production on pads, nose and eyes (regulated by B locus).

Dominant normal E allele allows production of eumelanin therefore, all homozygous (E/E) and heterozygous (E/e) dogs will be either black or other colour, if other loci are expressed (B, A and K-Locus).

Genotype

Description

E/E:

Dog is homozygous for normal allele; normal eumelanin production, expression of other loci can determine coat colour.

E/e:

Dog is heterozygous; because E allele is dominant eumelanin production is normal and expression of other loci can determine coat colour; dog is a carrier of recessive mutation and will transfer it to 50% of its offspring.

e/e:

Dog is homozygous for e allele; only pheomelanin is produced; dog expresses light cream to dark red coat colour.

Quantity:

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Opening hours:

Mon – Fri from 08:00 – 17:00

You can reach us by phone:

Mon – Fri from 10:00 – 12:00 and 14:00 - 16:00

Landline AT: +43 (0) 662 / 43 93 83
Landline DE: +49 (0) 8654 / 68 24 430

You can reach us by email:
support(at)feragen.at

Postal address:

Austria:
FERAGEN GmbH
 Laboratory for genetic veterinary diagnostics
Strubergasse 26
5020 Salzburg

Germany:
KUBEOS GmbH
 c/o FERAGEN
Niedervillern 8
83410 Running

The German address is a PO box. The samples are forwarded to our laboratory in Austria three times a week.

Please do not send items as "Registered", "Personally delivered", "Registered Mail" or as express mail. This will lead to delays or refusal of acceptance at the PO box.


If you would like one of these shipping options, send the sample directly to us in Austria.