{"product_id":"cerebellare-degeneration-mit-myositis-cdmc-nova-scotia-duck-tolling-retriever","title":"Cerebellar degeneration and myositis complex (CDMC) - Nova Scotia Duck Tolling Retriever","description":"\u003cp\u003eCerebellar degeneration and myositis complex (CDMC) is a disease that affects cerebellum (the area of brain that controls coordination and balance) and muscles. Also, the disease can involve other parts of the central nervous system, such as, the spinal cord, medulla oblongata, cerebral cortex and brain stem. Cerebellar degeneration is the result of inherited genetic mutations that affect the normal production of specific proteins necessary for the survival of neurons. Clinical symptoms of affected dogs are characteristic wide-based walk, neuromuscular weakness, tremor in the trunk of the body, loss of balance, tripping as well as falling. Other clinical signs may include episodes of marked movements during sleep, noise phobia, gait abnormalities and anxiety. The first symptoms start at 3 to 9 months of age. Affected dogs are usually euthanized prior to 2 years of age due to painful muscular degeneration.\u003c\/p\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eInheritance:\u003c\/strong\u003e \u003cem\u003eautosomal recessive\u003c\/em\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eMutation:\u003c\/strong\u003e SLC25A12 gene\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eGenetic test:\u003c\/strong\u003e The method used for genetic testing is extremely accurate and allows complete differentiation between affected animals, carriers and healthy dogs. DNA testing can be done at any age.\u003c\/p\u003e","brand":"EXT","offers":[{"title":"Default Title","offer_id":54113814872387,"sku":"2700029","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0674\/3189\/1218\/files\/FERAGEN_Einzelanalysen_48a05e0d-b0d9-4627-889d-6b492478be1e.jpg?v=1769440179","url":"https:\/\/shop.feragen.at\/en\/products\/cerebellare-degeneration-mit-myositis-cdmc-nova-scotia-duck-tolling-retriever","provider":"FERAGEN Shop","version":"1.0","type":"link"}